Cafestol
APC-978
Cafestol
Cat. No.
APC-978
CAS No.
469-83-0
MF
C20H28O3
MW
316.4
Cafestol is a diterpenoid and an inhibitor of ERK2.
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Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
469-83-0
MF
C20H28O3
MW
316.4
Specification
98%
Research Area
Anti-inflammatory, anti-angiogenic and anti-diabetic
Description
Cafestol is a diterpenoid and an inhibitor of ERK2. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Shen T, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32.
[2]. Wang S, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71.
[3]. Feng Y, et al. Cafestol inhibits colon cancer cell proliferation and tumor growth in xenograft mice by activating LKB1/AMPK/ULK1-dependent autophagy. J Nutr Biochem. 2024 Jul;129:109623.
[4]. Mellbye FB, et al. Cafestol, a Bioactive Substance in Coffee, Has Antidiabetic Properties in KKAy Mice. J Nat Prod. 2017 Aug 25;80(8):2353-2359.
Disclaimer
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